Ahhh, one of the reasons could be that Docker Desktop by default uses 50% of your RAM when they create their VM and the maximum amount of CPUs.
Podman Desktop by default has a much lower RAM (4GB) + CPU usage (50% CPU). That's something that could be improved... I've opened up an issue: https://github.com/podman-desktop/podman-desktop/issues/1634... :)
What sort of compatibility issues were you encountering? (disclaimer: I'm on the Podman Desktop team)
If it was compose + docker compatibility issues, that's on the roadmap for improvement :). Compose support is flakey at times (it's essentially a wrapper around the open source binary https://github.com/docker/compose)